It will be the 22nd career match-up between the two long-time rivals, who somehow have avoided each other at the US Open throughout their long careers.
Williams has just one professional tournament remaining before she drops the curtain on her historic career
'I'm terrible at goodbyes, the world's worst'
Tennis star Serena Williams says she is concerned about the Zika outbreak ahead of August's Rio Olympics, but has faith in the support team dealing with worries about the mosquito-carried virus.
Serena Williams was completely taken aback by her pregnancy, taking six home tests before believing she was expecting her first child, the tennis superstar told Vanity Fair magazine.
The unseeded Bencic, who also beat former world number ones Caroline Wozniacki and Ana Ivanovic in Toronto, wore a look of disbelief after the 18-year-old's forehand winner whizzed past Williams to seal the match.
Serena Williams took the first cautious step towards a record-equalling 24th Grand Slam title with a 6-4, 6-0 first-round win over Magda Linette.
Serena Williams' memory is not as powerful as her first serve these days, although with so many achievements to recall it would be churlish to hold that against the American great.
Frenchman Mouratoglou said Williams had been able to recharge during the break and that her appetite for titles had not waned.
For the second straight year Serena Williams saw her bid for a seventh U.S. Open title halted in the semi-finals with a 6-2 7-6(5) loss to Karolina Pliskova on Thursday that also ended her long reign as world number one.
Serena Williams was forced to dig deep to secure a 4-6, 6-3, 6-2 US Open quarter-final victory over unseeded Bulgarian Tsvetana Pironkova on Wednesday, keeping alive her latest bid for a record-tying 24th Grand Slam singles title.
With a 6-2, 6-1 3rd round win over Swedish Johanna Larsson at the US Open at Flushing Meadows on Saturday, Serena recorded her 307th Grand Slam victory and in doing so went past legendary Martina Novratilova to record the most wins in a major by a woman.
Top ranked Serena Williams won her third consecutive U.S. Open women's championship when she defeated Denmark's Caroline Wozniacki 6-3, 6-3 on Sunday.
'She wants to come back in 2018 and defend her title and she's in training now'
The 36-year-old American star stunned Paris this year in her body-hugging outfit which she said was inspired by the 'Black Panther' movie and made her feel like a 'warrior princess'.
Serena Williams sets up an all-American semi-final against teenager Madison Keys.
Coach Patrick Mouratoglou claimed Serena Williams' fitness had since gone up a notch and Margaret Court's all-time record of 24 Grand Slam singles titles may well be in peril at the Australian Open.
Serena Williams remains the 'queen' of women's tennis but don't be surprised if she's no longer No 1 by the end of the year, Martina Navratilova said Thursday.
Serena Williams kept her bid for a calendar-year Grand Slam on track, powering past big sister Venus 6-2, 1-6, 6-3 on a steamy star-studded night at the US Open in New York, on Tuesday.
Germany's experienced Angelique Kerber stands in the way of the 36-year-old American and an eighth, and arguably most impressive, All England Club singles crown which would see her match Margaret Court's all-time record of 24 Grand Slam titles.
The world No. 1 was beaten by Justine Henin-Hardenne in the final of the Family Circle Cup.
Playing her first match of the North American hard court swing after pulling out of last week's event in Stanford with a sore right elbow, Williams played a ragged opening set in which she was broken four times while firing four double faults.
Maria Sharapova's dreams of a sixth Grand Slam title were ended by Serena Williams and her wrecking ball serve in the Australian Open final on Saturday, but the Russian was adamant she would someday have the American's measure.
Serena Williams took some coaching advice from a fan during her fourth round match.
Serena Williams hopes her daughter Alexis Olympia does not want to follow in her mom's famous footsteps -- suggesting ice skating might be a good alternative.
Serena Williams likened the frustration she felt in Tuesday's shock defeat by Maria Sakkari at the Western and Southern Open to that of being stuck in a bad relationship.
'I think when I first started, you could win a lot of easy matches, then you're in the quarter-finals, that's when it starts to get a little more tough. Now, like, there's no easy match. Everyone's playing great. Everyone's just doing a lot better'
Serena Williams underlined the difference in class and power between her and the rest of the women's field with a 6-0, 6-4 demolition of fourth seed Agnieszka Radwanska on Thursday to reach her seventh Australian Open final.
Serena Williams creates ripples with her latest outfit.
Iga Swiatek survived a surprise U.S. Open second-round test on Thursday as men's top seed Jannik Sinner and Japan's four-times major winner Naomi Osaka cruised through.
Holder Serena Williams beat Justine Henin 6-2, 6-0 to reach the semi-finals of the Sony Ericsson Open.
Poland's Iga Swiatek could become only the third woman since tennis turned professional in 1968 to win all of her first six major finals, joining Margaret Court and Monica Seles, but Swiatek is not taking the big-hitting Anisimova lightly.
With no standout favourite in the women's field, it could provide an ideal stage for American Serena Williams to finally end her quest for an elusive 24th Grand Slam title.
Inspired Vinci rallies to beat World No 1 and then tells US crowd: 'But today is my day. Sorry guys'
Djokovic, Rafa Nadal and others who have complained about the blue clay at the Madrid Open are 'weenies', according to former Women's No. 1 Serena Williams.
World No 1 Serena Williams was handed the best possible draw for her WTA Finals title defence with the 33-year-old American grouped with two injury doubts and avoiding the in-form players.
The 20-year-old is on the longest unbeaten run in the women's tour since Serena Williams bagged 34 victories in succession in 2013.
It would be perfectly safe for Serena Williams to continue with rigorous training throughout pregnancy, but how quickly the 35-year-old would return to tournament tennis is uncertain.
Serena Williams' relaxed outlook on life spilled over even in defeat on Saturday when she appeared to be almost as happy that Angelique Kerber had won her first Grand Slam final as the German herself.